Tea consumption is related to a diminished threat of coronary heart illness, stroke, and untimely dying typically, with every further cup of inexperienced tea a day related to a 4-percent decrease mortality threat. So, maybe “drinking several cups of tea daily can keep the doctor away,” in addition to the mortician—however what about most cancers?
As I talk about in my video Can Green Tea Help Prevent Cancer, there’s “growing evidence from laboratory, epidemiologic [population], and human intervention studies that tea can exert beneficial disease-preventive effects” and, additional, may very well “slow cancer progression.” Let’s assessment a few of that proof.
Not solely do those that drink quite a lot of tea seem to reside longer than those that drink much less, as you may see at 0:49 in my video, consuming a lot of tea can also delay the onset of most cancers. At 0:56 in my video, you may see a desk titled “Average age at cancer onset and daily green tea consumption.” The inexperienced tea consumption is measured in Japanese tea cups, which solely comprise a half a cup, so the best class within the desk is definitely higher than or equal to 5 full cups of tea, not ten because it seems within the desk. Women who did get most cancers appeared to get it seven years later if that they had been consuming a lot of tea in contrast to those that had consumed much less. Men, nevertheless, had a three-year delay in most cancers onset if that they had consumed greater than 5 full cups of inexperienced tea day by day, the distinction doubtlessly “due to higher tobacco consumption by males.”
Green tea could find a way to intervene with every of the levels of most cancers formation: the initiation of the primary most cancers cell, promotion right into a tumor, and then subsequent development and unfold, as you may see at 1:24 in my video. Cancer is usually initiated when a free radical oxidizes our DNA, inflicting a mutation, however, as you may see at 1:44 in my video, we are able to get a pleasant “spike of antioxidant power” of our bloodstream inside 40 minutes of consuming inexperienced tea. “This increase may, in turn, lower oxidative damage to DNA and so decrease risk of cancer.”
Furthermore, when it comes to genoprotective results—that’s, defending our genes—pre-existing oxidation-induced DNA harm was decrease after consuming inexperienced tea, suggesting consumption can increase DNA restore as effectively. We didn’t know for sure, nevertheless…till now.
There is a DNA-repair enzyme in our physique known as OGG1. As you may see at 2:15 in my video, inside one hour of consuming a single cup of inexperienced tea, we are able to increase OGG1’s exercise, and after per week of tea consuming, we are able to increase it even greater. So, “regular intake of green tea has additional benefits in the prevention and/or repair of DNA damage.” In truth, tea is so DNA-protective it may be used for sperm storage for recent samples till they are often correctly refrigerated.
What’s extra, tea is so anti-inflammatory it may be used for ache management as a mouthwash after knowledge tooth surgical procedure, as you may see at 2:41 in my video. In phrases of controlling most cancers development, at a dose of inexperienced tea compounds that might make it into our organs after consuming six cups of tea, it will possibly trigger most cancers cells to commit suicide—apoptosis (programmed cell dying)—whereas leaving regular cells alone. There are various chemotherapy brokers that may kill most cancers by way of brute power, however that may make regular cells weak, too. So, “[g]reen tea appears to be potentially an ideal agent for [cancer] prevention”: little or no adversarial side-effects, efficacious for a number of cancers at achievable dose ranges, and in a position to be taken orally. We have a way of the way it works—the way it stops most cancers cells from rising and inflicting them to kill off themselves—and it’s low cost and has a historical past of secure, acceptable use. But, all of this was based mostly on in-vitro research in a take a look at tube. “It needs to be evaluated in human trials,” concluded the researchers. Indeed, what occurs once we give inexperienced tea to folks with most cancers? Does it assist?
Tea consumption could scale back the danger of getting oral most cancers. Not solely could the consumption of tea increase the antioxidant energy of our bloodstream inside minutes and lower the quantity of free-radical DNA harm all through our techniques over time, however it will possibly additionally enhance the antioxidant energy of our saliva and lower the DNA harm inside the inside cheek cells of people who smoke, although not as a lot as stopping smoking all collectively. You can see a number of graphs and tables displaying these findings within the first 35 seconds of my video Can Green Tea Help Treat Cancer?.
Might this assist precancerous oral lesions from turning into cancerous oral lesions? More than 100,000 folks develop oral most cancers yearly worldwide, with a five-year general survival charge of lower than the flip of a coin. Oral most cancers continuously arises from precancerous lesions within the mouth, every having a number of % likelihood of turning cancerous yearly. Can inexperienced tea assist?
Fifty-nine sufferers with precancerous oral lesions have been randomized into both a tea group, wherein capsules of powdered tea extract got and their lesions have been painted with inexperienced tea powder, or a management group, who basically received sugar drugs and their lesions painted with nothing however glycerin. As you may see at 1:23 in my video, inside six months, lesions in 11 out of the 29 within the tea group shrunk, in contrast to solely 3 of 30 within the placebo group. “The results indicate that tea treatment can improve the clinical manifestations of the oral lesions.”
The most vital query, although, is whether or not the tea remedy prevented the lesions from turning cancerous. Because the trial solely lasted a number of months, the researchers couldn’t inform. When they scraped some cells off of the lesions, nevertheless, there was a major drop in DNA-damaged cells inside three months within the remedy teams, suggesting that issues have been moving into the correct route, as you may see at 1:46 in my video. Ideally, we’d have an extended research to see in the event that they ended up with much less most cancers and one which simply used swallowed tea parts, since most individuals don’t finger-paint with tea of their mouths. And, we received simply that.
As you may see at 2:15 in my video, there have been the identical extraordinary medical outcomes with some precancerous lesions shrinking away. What’s extra, the research lasted lengthy sufficient to see if fewer folks truly received most cancers. The reply? There was simply as a lot new most cancers within the inexperienced tea group because the placebo group. So, the tea remedy resulted in the next response charge, because the lesions regarded higher, however there was no enchancment in cancer-free survival.
These research have been executed on largely people who smoke and former people who smoke. What about lung most cancers? As you may see at 2:46 in my video, inhabitants research recommend tea could also be protecting, however let’s put it to the take a look at. Seventeen sufferers with superior lung most cancers got up to the equal of 30 cups of inexperienced tea a day, however “[n]o objective responses were seen.” In a research of 49 most cancers sufferers, 21 of whom had lung most cancers, the topics acquired between 4 and 25 cups value of inexperienced tea compounds a day. Once once more, no advantages have been discovered. The solely profit inexperienced tea could find a way to provide lung most cancers sufferers is to assist reduce the burns from the radiation remedies when utilized on the pores and skin. Indeed, inexperienced tea compresses could find a way to shorten the length of the burns, as you may see at 3:21 in my video.
The protecting results of inexperienced tea utilized topically have been additionally seen in precancerous cervical lesions, the place the twice-a-day direct utility of a inexperienced tea ointment confirmed a useful response in practically three-quarters of the sufferers, in contrast to solely about 10 % within the untreated management group, which is according to the advantages of inexperienced tea compounds on cervical most cancers cells in a petri dish. When girls got inexperienced tea extract drugs to take, nevertheless, they didn’t appear to assist.
I talked in regards to the potential good thing about inexperienced tea wraps for pores and skin most cancers in Treating Gorlin Syndrome with Green Tea, however is there every other most cancers the place inexperienced tea can come into direct contact? Yes. Colon most cancers, which grows from the inside floor of the colon that comes into contact with food and drink. As you may see at 4:13 in my video, within the colon, tea compounds are fermented by our good intestine micro organism into compounds like 3,4DHPA, which seems to wipe out colon most cancers cells, whereas leaving regular colon cells comparatively intact in vitro. So 100 thirty-six sufferers with a historical past of polyps have been randomized to get inexperienced tea extract drugs or not. Now, this research was executed in Japan, the place consuming inexperienced tea is commonplace, so, successfully, this was evaluating those that drank three cups of inexperienced tea a day to topics who drank 4 day by day cups. A yr in a while colonoscopy, the added-green tea group had solely half the polyp recurrence and the polyps that did develop have been 25 % smaller. With such thrilling findings, why hasn’t a bigger follow-up research been executed? Perhaps due to the problem “in raising funds” for the research, “because green tea is a beverage but not a pharmaceutical.”
There is nice information. Thanks to a significant most cancers charity in Germany, researchers are at present recruiting for the biggest inexperienced tea most cancers trial to date, wherein greater than 2,000 sufferers might be randomized. I look ahead to presenting the outcomes to you once they are available.
What about prostate most cancers? See my movies Preventing Prostate Cancer with Green Tea and Treating Prostate Cancer with Green Tea.
You can also be thinking about these considerably older movies:
How attention-grabbing was that about knowledge enamel? Green tea may also be used as an anti-cavity mouth rinse, which I talk about in my video What’s the Best Mouthwash?.
Is Caffeinated Tea Dehydrating? Watch the video to discover out.
Michael Greger, M.D.
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