What is the medical relevance of vitamin C amongst lead-exposed infertile males? Compared to controls, lead battery trade employees given 1,000 mg of vitamin C each workday for three months skilled “a significant increase in sperm motility and sperm count, as well as decrease in abnormal sperm,” and “a significant reduction in the incidence of sperm DNA fragmentation,” that’s, broken sperm DNA. Okay, however the splendid endpoint could be bouncing baby boys and girls. Enter this extraordinary little research from the University of Texas from greater than 30 years in the past.
Twenty-seven males with fertile wives had been attempting to have children for years to no avail. Twenty of them got 1,000 mg of vitamin C a day for two months, and 7 acted as controls and didn’t get any vitamin C. The researchers adopted up on the finish of the 60 days. By then, each single one of many wives of every of the 20 males who had gotten the vitamin C had grew to become pregnant—20 out of 20! After years of frustration, increase: 100-percent pregnant. What’s extra, not a single one of many wives of males within the management group obtained pregnant. Rarely does one see these sorts of black-and-white ends in the medical literature for any intervention.
Is the vitamin C reducing the oxidative stress from the lead, or is it really reducing the stage of lead? Sure, antioxidant supplementation can have antioxidant results, however it might fail to really decrease lead ranges within the blood. Now, this was in a body of workers who had been respiratory lead day in and day trip, and the way in which vitamin C may match is by merely blocking the “intestinal absorption of lead.” An earlier research confirmed vitamin C supplementation apparently lower lead ranges by a 3rd inside six months, however that was with a whopping dose of 2 g with added zinc. Another small research discovered the identical 30 % drop with simply 500 mg a day, no zinc, and in just one month. But neither of these research had a management group of topics who didn’t take something, so we don’t know if their ranges would have fallen anyway.
Similarly, there’s an nearly too-good-to-be-true research on the position of vitamin C in scavenging lead toxicity from “biosystems,” by which they meant youngsters. They obtained 250 to 500 mg a day of vitamin C for just a few months, and shaved hair samples each month noticed as much as a 69 % decline in lead ranges. Researchers repeated it in two different small teams of children and noticed the identical wonderful type of drops in each single youngster. But possibly lead ranges had been simply dropping all through the entire neighborhood throughout that point? Without measuring lead ranges in a management group of children not taking vitamin C, we will’t ensure.
As I illustrate from 3:17 in my video Yellow Bell Peppers for Male Infertility and Lead Poisoning?, with eight weeks of vitamin C, lead ranges dropped within the blood and rose within the urine. One may conclude that the vitamin C was pulling lead out of the physique, however the identical factor occurred within the placebo group: Blood ranges dropped, and urine ranges rose. So, it had nothing to do with the vitamin C in any respect. That’s why it’s all the time necessary to have a management group.
The similar applies with research that appeared to point out no profit. For instance, 36 battery manufacturing employees had been studied. Each was given vitamin C, but there was no change of their lead ranges. But, possibly their co-workers suffered a giant improve in lead ranges throughout that very same time interval, and the vitamin C was really profitable in conserving the topics’ ranges from rising. You don’t know and not using a management group.
That’s why research like “The effects of vitamin C supplementation on blood and hair levels of cadmium, lead, and mercury” are so necessary. Vitamin C versus an identical-looking sugar tablet placebo. The consequence? The vitamin C failed to assist, which actually put a damper on enthusiasm for utilizing vitamin C for lead poisoning till a now-famous research was printed in 1999 that confirmed that vitamin C supplementation may result in a lower in blood ranges. As you possibly can see at 4:32 in my video, after 4 weeks of taking a placebo, not a lot change occurred in blood lead ranges within the management group, which is what we’d anticipate. In distinction, the vitamin C group started out at about the identical blood lead stage because the management group, however inside one week of taking 1,000 mg of vitamin C a day, lead ranges dropped 81 %. So, supplementation of vitamin C “may provide an economical and convenient method of reducing blood-lead levels, possibly by reducing the intestinal absorption of lead.”
The urine lead ranges didn’t change, so it’s not as if the topics had been excreting extra lead of their urine to convey down their blood ranges. However, a lot of the lead in our blood is within the crimson blood cells, that are recycled within the liver and discharged by the bile into the intestine the place the lead may simply get reabsorbed—except, maybe, you’ve obtained loads of vitamin C in there to dam the re-absorption. But 1,000 mg is loads of vitamin C. Would one thing like 200 mg, which is nearly how a lot vitamin C you’d get in an orange and a cup of broccoli or strawberries, work? The researchers examined that, too. The 200 mg group started out the identical because the management and the 1,000 mg group, however blood lead ranges didn’t actually budge. Bummer! So, 1,000 mg appeared to work, however 200 mg didn’t. Isn’t 1,000 mg of vitamin C a bit unnatural, although? The RDA is barely 60 mg. Well, really, we might have advanced for thousands and thousands of years getting nearer to 600 mg a day—ten occasions the present RDA—as a result of we had been eating so many fruits and greens. Okay, however may you attain 1,000 mg of vitamin C with out having to take drugs? Yes! That’s the quantity of vitamin C, for instance, that may be present in three yellow bell peppers.
Other movies in my sequence on lead embrace:
- Is Lipstick Safe Given the Lead Contamination?
- Can Saunas Detoxify Lead from the Body?
- How the Lead Paint Industry Got Away with It
- Lead in Drinking Water
- How the Leaded Gas Industry Got Away with It
- “Normal” Blood Lead Levels Can Be Toxic
- The Effects of Low-Level Lead Exposure in Adults
- How to Lower Lead Levels with Diet: Thiamine, Fiber, Iron, Fat, Fasting?
- How to Lower Lead Levels with Diet: Breakfast, Whole Grains, Milk, Tofu?
- Best Foods for Lead Poisoning: Chlorella, Cilantro, Tomatoes, Moringa?
- Best Food for Lead Poisoning: Garlic
- Can Vitamin C Help with Lead Poisoning?
- How Much Lead Is in Organic Chicken Soup (Bone Broth)?
- Lead in Calcium Supplements
- Should Pregnant Women Take Calcium Supplements to Lower Lead Levels?
- The Rise in Blood Lead Levels at Pregnancy and Menopause
- Lead Contamination in Fish and Game
- Lead Contamination in Hot Sauces
Note that there’s nothing particular about yellow bell peppers—aside from their extraordinary vitamin C content material, that’s. I simply used them as a sensible strategy to get 1,000 mg of vitamin C in whole-food kind. They’re definitely simpler than eating ten oranges!
Though, keep in mind my video Peppers and Parkinson’s: The Benefits of Smoking Without the Risks? So, one would anticipate to get all the advantages of the 1,000 mg of vitamin C with advantages. Why not simply take vitamin C dietary supplements? See Do Vitamin C Supplements Prevent Colds however Cause Kidney Stones?.
If a whole lot of milligrams a day of vitamin C seems like so much, try What Is the Optimal Vitamin C consumption?.
You could also be excited by my vitamin C and most cancers sequence:
Finally, for extra on male fertility, see:
Michael Greger, M.D.
PS: If you haven’t but, you possibly can subscribe to my free movies right here and watch my reside displays: