What’s the most recent on treating depression with the spice saffron? Years in the past, I lined a head-to-head comparability of saffron versus Prozac for the therapy of depression in my video Saffron vs. Prozac, and saffron appeared to work simply in addition to the drug. In the years since, 5 different research have discovered that saffron beat out placebo or rivaled antidepressant medicines.
It could be the spice’s purple pigment, crocin, since that alone beat out placebo as an adjunct therapy, considerably reducing signs of depression, signs of hysteria, and normal psychological misery. Perhaps, its antioxidants performed a task in “preventing free radical-induced damage in the brain.” The quantity of crocin the researchers used was equal to a couple of half teaspoon of saffron a day.
If the spice works in addition to the medication, one may argue that the spice wins, because it doesn’t trigger sexual dysfunction within the majority of women and men like most prescribed antidepressants do. SSRI medication like Prozac, Paxil, and Zoloft trigger “adverse sexual side effects” in round 70 p.c of individuals taking them. What’s extra, physicians not solely considerably underestimate the prevalence of unwanted effects, however additionally they are likely to underrate how a lot they impression the lives of their sufferers.
Not solely is that this not an issue with saffron, the spice could even have the ability to deal with it, as I discover in my video Best Food for Antidepressant-Induced Sexual Dysfunction. “In folks drugs, there is a extensively held perception that saffron might need aphrodisiac results.” To check this, males with Prozac-induced sexual impairment have been randomized to saffron or placebo for a month. By week 4, the saffron group “resulted in significantly greater improvement in erectile function…and intercourse satisfaction,” and greater than half of the lads within the saffron group regained “normal erectile function.” The researchers concluded that saffron is an “efficacious treatment” for Prozac-related erectile dysfunction. It has all been discovered to be efficient for feminine sexual dysfunction, as nicely, as you’ll be able to see at 2:35 in my video. Female sexual operate elevated by week 4, bettering a number of the Prozac-induced sexual issues however not others. So, it could be higher to attempt saffron within the first place for the depression and keep away from creating these sexual dysfunction issues, since they often can persist even after stopping the medication, doubtlessly worsening one’s long-term depression prognosis.
This contains uncommon unwanted effects, akin to genital anesthesia, the place you actually lose sensation. It can occur in women and men. More hardly ever, antidepressants can induce a situation referred to as stressed genital syndrome. You’ve heard of stressed legs syndrome? Well, it is a stressed between-the-legs syndrome. These PSSDs, or Post-SSRI Sexual Dysfunctions, which means dysfunctions that seem or persist after stopping taking these antidepressants, could be so critical that “prescribing physicians should mention the potential danger of the occurrence of genital (e.g., penile or vaginal) anesthesia to every patient prior to any SSRI treatment.” If you’re on one among these medication, did your physician warn you about that?
All hope isn’t misplaced, although. Evidently, penile anesthesia responds to low-power laser irradiation. After 20 laser remedies to his penis, one man, who had misplaced his penile sensation due to the drug Paxil, partially regained his “penile touch and temperature sensation.” However, he nonetheless couldn’t carry out to his girlfriend’s satisfaction, and he or she evidently ended up leaving him over it, which definitely didn’t assist his temper. But, earlier than you’re feeling too badly for him, examine a bit penile mild remedy to clitoridectomy, clitoris elimination surgical procedure, or one other Paxil-related case the place a lady’s signs solely improved after six programs of electroshock remedy.
Pass the paella!
For extra on the spice, take a look at:
Those drug unwanted effects sound devastating, however depression is not any stroll within the park. However, when one balances threat and profit, one assumes that there are truly advantages to taking them. That’s why the stunning science I explored in Do Antidepressant Drugs Really Work? is so essential.
What else could enhance temper? A healthy weight loss program and exercise:
For extra on sexual health typically, see:
What else can spices do? Here’s only a style:
Michael Greger, M.D.
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